SCHEMBL15079892

SCHEMBL15079892

COc1ccccc1OCCc1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
JAK2 O60674 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
MPO P05164 2/20 0.53
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
ADRB2 P07550 3/20 0.49
DRD2 P14416 1/20 0.49
DRD1 P21728 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19825667 0.91 MAPT (0.63) LMNAJAK2GAAMAPTMPO
SCHEMBL897950 0.85 GAA (0.67) LMNAJAK2GAAMAPTMPO
SCHEMBL15079786 0.83 LMNA (0.48) LMNAJAK2GAAMAPTTSHR
SCHEMBL8704419 0.82 MPO (0.68) LMNAMAPTMPOCA1CA2
SCHEMBL18798720 0.81 KDM4E (0.42) LMNAJAK2GAAMAPTMPO
SCHEMBL15079871 0.79 MAPT (0.51) LMNAGAAMAPTTP53DRD2
SCHEMBL2909007 0.79 TAAR1 (0.53) LMNAGAACA1CA2L3MBTL1
SCHEMBL15079783 0.79 MPO (0.49) LMNAJAK2GAAMAPTMPO
SCHEMBL8704875 0.79 MPO (0.69) MAPTMPOCA1CA2TP53
SCHEMBL2772333 0.77 TAAR1 (0.54) MPOTSHRNPC1PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 LMNA 2346/4885JAK2 3299/4885GAA 2119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.