Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694594 | 0.84 | LMNA (0.32) | LMNA | |
| SCHEMBL16405721 | 0.83 | CTSK (0.33) | LMNA | |
| SCHEMBL23037193 | 0.79 | CYP2C19 (0.34) | LMNA | |
| SCHEMBL20488331 | 0.78 | OPRM1 (0.41) | — | |
| SCHEMBL27774079 | 0.77 | CYP2C19 (0.35) | LMNA | |
| SCHEMBL7384094 | 0.76 | HCRTR2 (0.39) | LMNA | |
| SCHEMBL27617860 | 0.75 | — | — | |
| SCHEMBL23538470 | 0.74 | CYP2C19 (0.37) | — | |
| SCHEMBL23593484 | 0.74 | TDP1 (0.42) | LMNA | |
| SCHEMBL23538650 | 0.73 | P2RX7 (0.34) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490186-A | Compounds for targeted degradation of RET | C4医药公司 | 2023-07-25 | — | — | CN | disclosed |