Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 7/20 | 0.71 |
| ▸ | PLAU | P00749 | 6/20 | 0.71 |
| ▸ | SLC22A1 | O15245 | 6/20 | 0.71 |
| ▸ | SLC22A3 | O75751 | 6/20 | 0.71 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.71 |
| ▸ | HTR3B | O95264 | 5/20 | 0.71 |
| ▸ | HTR3A | P46098 | 5/20 | 0.71 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.71 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.71 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylguanidine SCHEMBL467577 | 0.84 | SLC22A2 (1.00) | SLC22A2PLAUSLC22A1SLC22A3HTR3E | |
| Phenylguanidine SCHEMBL4739913 | 0.82 | SLC22A2 (0.94) | SLC22A2PLAUSLC22A1SLC22A3HTR3E | |
| Phenylguanidine SCHEMBL11092912 | 0.82 | SLC22A2 (0.94) | SLC22A2PLAUSLC22A1SLC22A3HTR3E | |
| Phenylguanidine SCHEMBL28899228 | 0.78 | SLC22A2 (0.85) | SLC22A2PLAUSLC22A1SLC22A3HTR3E | |
| Pyraxinine SCHEMBL2456850 | 0.77 | HTR3E (1.00) | SLC22A2PLAUSLC22A1SLC22A3HTR3E | |
| Phenylguanidine SCHEMBL6129042 | 0.75 | PLAU (0.71) | SLC22A2PLAUSLC22A1SLC22A3HTR3E | |
| SCHEMBL164098 | 0.75 | PLG (1.00) | SLC22A2PLAUSLC22A1SLC22A3HTR3E | |
| Azobenzene SCHEMBL28277084 | 0.75 | ALDH1A1 (0.63) | HTR3APOLBCYP2C19LMNACYP1A2 | |
| Azobenzene SCHEMBL28277082 | 0.75 | ALDH1A1 (0.63) | HTR3APOLBCYP2C19LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL11099753 | 0.73 | PLG (0.95) | SLC22A2PLAUSLC22A1SLC22A3HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924998-A | Preparation method and application of substituted phenyl pyrimidine guanidine compound | 沈阳农业大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116924998-A | Preparation method and application of substituted phenyl pyrimidine guanidine compound | 沈阳农业大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116924998-A | Preparation method and application of substituted phenyl pyrimidine guanidine compound | 沈阳农业大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116924998-A | Preparation method and application of substituted phenyl pyrimidine guanidine compound | 沈阳农业大学 | 2023-10-24 | — | — | CN | disclosed |