Phenylguanidine

Phenylguanidine

SCHEMBL467577

NC(N)=Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 7/20 1.00
SLC22A1 O15245 6/20 1.00
SLC22A3 O75751 6/20 1.00
PLAU P00749 5/20 1.00
HTR3E A5X5Y0 4/20 1.00
HTR3B O95264 4/20 1.00
HTR3A P46098 4/20 1.00
HTR3D Q70Z44 4/20 1.00
HTR3C Q8WXA8 4/20 1.00
POLB P06746 1/20 0.72
NOS1 P29475 3/20 0.67
NOS3 P29474 2/20 0.67
CYP2C19 P33261 2/20 0.65
LMNA P02545 1/20 0.65
CYP1A2 P05177 1/20 0.65
ALOX15 P16050 1/20 0.65
NFKB1 P19838 1/20 0.65
BLM P54132 1/20 0.65
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylguanidine SCHEMBL11092912 0.97 SLC22A2 (0.94) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Phenylguanidine SCHEMBL4739913 0.97 SLC22A2 (0.94) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Phenylguanidine SCHEMBL28899228 0.92 SLC22A2 (0.85) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Phenylguanidine SCHEMBL29091382 0.84 SLC22A2 (0.71) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Phenylguanidine SCHEMBL6129042 0.84 PLAU (0.71) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL6273560 0.80 NOS1 (1.00) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL3785375 0.80 NOS1 (1.00) SLC22A2SLC22A1SLC22A3PLAUHTR3E
SCHEMBL7448212 0.80 NOS1 (1.00) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Phenyl Biguanide SCHEMBL19038542 0.79 HTR3E (1.00) SLC22A2SLC22A1SLC22A3PLAUHTR3E
Phenyl Biguanide SCHEMBL30226327 0.79 HTR3E (1.00) SLC22A2SLC22A1SLC22A3PLAUHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12447645-B2 Modified timber GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS (DE) 2025-10-21 US claimed
CN-120022762-A Nanofiltration composite membrane and preparation method and application thereof 中国科学院大连化学物理研究所 2025-05-23 CN claimed
CN-117865165-B Preparation method and application of ultra-small particle and high-stability silicon dioxide colloid 山东科翰硅源新材料有限公司 2024-09-17 CN claimed
EP-4031338-B1 MODIFIED TIMBER GEORG AUGUST UNIV GOETTINGEN (DE) 2024-07-31 EP claimed
CN-117865165-A Preparation method and application of ultra-small particle and high-stability silicon dioxide colloid 山东科翰硅源新材料有限公司 2024-04-12 CN claimed
CN-117539135-A Corrosion-free photoresist stripper 南通群安电子材料有限公司 2024-02-09 CN claimed
CN-116510525-B High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-09-01 CN claimed
CN-116510525-A High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-08-01 CN claimed
EP-3795317-B1 MODIFIED TIMBER GEORG AUGUST UNIV GOETTINGEN (DE) 2023-06-07 EP claimed
US-20220379517-A1 MODIFIED TIMBER GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS (DE) 2022-12-01 US claimed
US-4486356-A BY-PRODUCT INHIBITION GESHURI LABORATORIES, LTD. (IL) 1984-12-04 US claimed
WO-1984004455-A1 POTENTIATION OF ANTHELMINTICS COMMW SCIENT IND RES ORG (AU) 1984-11-22 WO claimed
EP-0018134-B1 DIHYDROPYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1984-03-14 EP claimed
EP-0098034-A2 A process for producing n-phosphonomethylglycine derivatives and herbicidal compounds and compositions prepared thereby Geshuri Laboratories Ltd. (IL) 1984-01-11 EP claimed
US-4404219-A ORAL HYPOGLYCEMIC AGENTS; DIABETES PFIZER INC. (US) 1983-09-13 US claimed
US-4293690-A PROTECTING HYDROXYLS OF 5-AMINO-1-B-D-RIBOFURANOSYLIMIDAZOLE-4-CARBOXAMIDE, DEHYDRATION, CYCLIZATION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-06 US claimed
US-4281004-A FOR TREATMENT OF DIABETES PFIZER INC. (US) 1981-07-28 US claimed
EP-0017465-A1 Production of 2,6-diaminonebularines Takeda Chemical Industries, Ltd. (JP) 1980-10-15 EP claimed
US-4176192-A ANTHELMINTICS HOECHST AKTIENGESELLSCHAFT (DE) 1979-11-27 US claimed
US-3976787-A VASOCONSTRICTION ARMOUR PHARMACEUTICAL COMPANY (US) 1976-08-24 US claimed