Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295502 | 0.83 | APP (0.34) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL29091582 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBNFKB1MEN1 | |
| SCHEMBL29091614 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| SCHEMBL2919013 | 0.74 | EPRS1 (0.37) | POLB | |
| SCHEMBL29091596 | 0.73 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29091657 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4171115 | 0.72 | CCNB2 (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4171109 | 0.72 | — | — | |
| SCHEMBL27296836 | 0.70 | MAPT (0.35) | KDM4EMAPT | |
| SCHEMBL2148737 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4EPOLBNFKB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |