Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067133 | 1.00 | ALOX15 (0.44) | ALOX15CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16244319 | 1.00 | ALOX15 (0.44) | ALOX15CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14775484 | 0.83 | ALDH1A1 (0.40) | ALOX15TSHRFAAHSOAT1CYP3A4 | |
| SCHEMBL16244148 | 0.82 | ADORA3 (0.51) | ALOX15CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7555801 | 0.81 | ALDH1A1 (0.52) | ALOX15CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9540438 | 0.81 | NR1I2 (0.38) | ALOX15TSHRFAAHCYP3A4NR1I2 | |
| SCHEMBL9540436 | 0.81 | NR1I2 (0.38) | ALOX15TSHRFAAHCYP3A4NR1I2 | |
| SCHEMBL31548 | 0.81 | ALDH1A1 (0.52) | ALOX15CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9782649 | 0.81 | ALDH1A1 (0.52) | ALOX15CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9540440 | 0.81 | PGR (0.38) | ALOX15CHRM1LMNACYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582485-B | Pyrazole derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-13 | — | — | CN | disclosed |