Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 5/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093852 | 0.83 | HTR2A (0.35) | HDAC1HDAC6CCR2 | |
| SCHEMBL29093827 | 0.80 | BTK (0.41) | KMOALDH1A1 | |
| SCHEMBL29094009 | 0.80 | KMO (0.40) | HDAC1HDAC8HDAC6KMOKDM4E | |
| SCHEMBL29093825 | 0.76 | ALDH1A1 (0.35) | KMOKDM4EALDH1A1 | |
| SCHEMBL29093832 | 0.75 | HTR2A (0.34) | HDAC1HDAC6ALDH1A1 | |
| SCHEMBL29094005 | 0.75 | HTR2A (0.35) | KDM4EALDH1A1CCR2CYP11B2 | |
| SCHEMBL29093861 | 0.73 | BTK (0.40) | KMOKDM4EALDH1A1 | |
| SCHEMBL29093857 | 0.73 | KMO (0.40) | MAT2AKMOKDM4EALDH1A1 | |
| SCHEMBL29093829 | 0.73 | KMO (0.39) | HDAC1HDAC8HDAC6KMOALDH1A1 | |
| SCHEMBL29094004 | 0.72 | ADORA2A (0.36) | HDAC8KMOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572300-A | Synthesis method of sulfonamide substituted polycyclic quinazolinone compound | 江苏理工学院 | 2023-01-06 | — | — | CN | disclosed |