Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SIK1 | P57059 | 2/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094009 | 0.92 | KMO (0.40) | KMOFGFR1FGFR4CNR1CNR2 | |
| SCHEMBL29093857 | 0.84 | KMO (0.40) | KMOALDH1A1SIK1SIK2SIK3 | |
| SCHEMBL29093832 | 0.84 | HTR2A (0.34) | ALDH1A1SIK1SIK2SIK3SMN1; SMN2 | |
| SCHEMBL29093861 | 0.84 | BTK (0.40) | KMOALDH1A1NPC1THRBKMT2A | |
| SCHEMBL29094004 | 0.81 | ADORA2A (0.36) | KMOCNR1CNR2ALDH1A1NPC1 | |
| SCHEMBL29094008 | 0.81 | TLR8 (0.37) | KMOFGFR1FGFR4ALDH1A1NPC1 | |
| SCHEMBL29094002 | 0.76 | PGR (0.38) | KMOALDH1A1NPC1KMT2AHSD17B10 | |
| SCHEMBL29093852 | 0.76 | HTR2A (0.35) | BTKADORA2AADORA1HDAC1HDAC6 | |
| SCHEMBL29093827 | 0.76 | BTK (0.41) | KMOALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL29093825 | 0.72 | ALDH1A1 (0.35) | KMOCNR2ALDH1A1SMN1; SMN2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572300-A | Synthesis method of sulfonamide substituted polycyclic quinazolinone compound | 江苏理工学院 | 2023-01-06 | — | — | CN | disclosed |