Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 7/20 | 0.40 |
| ▸ | MAT2A | P31153 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | SIK1 | P57059 | 1/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093829 | 0.84 | KMO (0.39) | KMOSIK1SIK2SIK3SMN1; SMN2 | |
| SCHEMBL29093861 | 0.84 | BTK (0.40) | KMOHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29093832 | 0.84 | HTR2A (0.34) | SIK1SIK2SIK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL29094008 | 0.81 | TLR8 (0.37) | KMOSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL29094002 | 0.76 | PGR (0.38) | KMOHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29094009 | 0.76 | KMO (0.40) | KMOCCR9HTTSMN1; SMN2KDM4E | |
| SCHEMBL29093827 | 0.76 | BTK (0.41) | KMOHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29093852 | 0.76 | HTR2A (0.35) | — | |
| SCHEMBL15283315 | 0.73 | TMEM97 (0.63) | TMEM97SMN1; SMN2 | |
| SCHEMBL29093828 | 0.73 | HDAC1 (0.39) | KMOMAT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572300-A | Synthesis method of sulfonamide substituted polycyclic quinazolinone compound | 江苏理工学院 | 2023-01-06 | — | — | CN | disclosed |