Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093861 | 0.90 | BTK (0.40) | PGRRORARORCRORBTLR8 | |
| SCHEMBL29093827 | 0.81 | BTK (0.41) | HTTTP53HSD17B10ALDH1A1BTK | |
| SCHEMBL29094008 | 0.81 | TLR8 (0.37) | PGRRORARORCRORBTLR8 | |
| SCHEMBL29093829 | 0.76 | KMO (0.39) | HSD17B10ALDH1A1BTKSMN1; SMN2KMO | |
| SCHEMBL29093824 | 0.76 | SYK (0.33) | HTTTP53HSD17B10KDM4EALDH1A1 | |
| SCHEMBL29093832 | 0.76 | HTR2A (0.34) | ALDH1A1BTKSMN1; SMN2MAPTGAA | |
| SCHEMBL29093857 | 0.76 | KMO (0.40) | HTTKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29093834 | 0.76 | TLR8 (0.39) | TLR8KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29094005 | 0.76 | HTR2A (0.35) | HSD17B10KDM4EALDH1A1BTKMAPT | |
| SCHEMBL29094004 | 0.76 | ADORA2A (0.36) | HTTHSD17B10ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572300-A | Synthesis method of sulfonamide substituted polycyclic quinazolinone compound | 江苏理工学院 | 2023-01-06 | — | — | CN | disclosed |