Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382199 | 0.84 | RAPGEF4 (0.40) | IDO1IDH1NOTUM | |
| SCHEMBL25298504 | 0.84 | RAPGEF4 (0.40) | IDO1IDH1NOTUM | |
| SCHEMBL12883518 | 0.80 | IDO1 (0.39) | IDO1MAOBKDM1AKCNH2KDM1B | |
| SCHEMBL31071619 | 0.80 | AR (0.37) | IDH1 | |
| SCHEMBL15506539 | 0.80 | AR (0.37) | IDH1 | |
| SCHEMBL22117744 | 0.77 | ALOX15 (0.40) | IDO1 | |
| SCHEMBL16938860 | 0.75 | ABCC9 (0.40) | MAOB | |
| SCHEMBL11939279 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL25249405 | 0.74 | POLB (0.46) | IDO1 | |
| SCHEMBL21788380 | 0.74 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891457-A | Chimeric compound for androgen receptor protein targeted degradation, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-10-17 | — | — | CN | disclosed |