SCHEMBL29096004 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	5/20	0.40

▸	ALDH1A1	P00352	4/20	0.40

▸	HPGD	P15428	1/20	0.40

▸	MAPT	P10636	6/20	0.39

▸	ALOX15	P16050	2/20	0.39

▸	HSD17B10	Q99714	1/20	0.39

▸	LMNA	P02545	3/20	0.39

▸	MAPK1	P28482	1/20	0.39

▸	PTGS2	P35354	5/20	0.39

▸	POLB	P06746	3/20	0.38

▸	L3MBTL1	Q9Y468	2/20	0.38

▸	TP53	P04637	1/20	0.38

▸	HIF1A	Q16665	1/20	0.38

▸	TDP1	Q9NUW8	1/20	0.38

▸	KDM4E	B2RXH2	1/20	0.38

▸	GAA	P10253	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29630214	1.00	TSHR (0.40)	TSHRALDH1A1HPGDMAPTALOX15
SCHEMBL29630194	0.89	SLC26A4 (0.36)	LMNAPOLBL3MBTL1
SCHEMBL29095745	0.89	SLC26A4 (0.36)	LMNAPOLBL3MBTL1
SCHEMBL29095791	0.85	LMNA (0.43)	TSHRALDH1A1MAPTALOX15HSD17B10
SCHEMBL29630220	0.85	LMNA (0.43)	TSHRALDH1A1MAPTALOX15HSD17B10
SCHEMBL24470679	0.81	ALOX15 (0.51)	TSHRALDH1A1HPGDALOX15PTGS2
SCHEMBL29630204	0.81	ALOX15 (0.51)	TSHRALDH1A1HPGDALOX15PTGS2
SCHEMBL29095727	0.81	TSHR (0.47)	TSHRALDH1A1MAPTLMNAMAPK1
SCHEMBL29630222	0.79	TSHR (0.51)	TSHRALDH1A1MAPTLMNAMAPK1
SCHEMBL29096031	0.79	TSHR (0.51)	TSHRALDH1A1MAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116745283-A	Heterocyclic derivatives for the treatment of TRPM3 mediated disorders	勒芬天主教大学	2023-09-12	—	—	CN	disclosed