Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29095791 | 1.00 | LMNA (0.43) | LMNAL3MBTL1MAPK1KDM4EHTT | |
| SCHEMBL29630239 | 0.89 | LMNA (0.42) | LMNAL3MBTL1MAPK1KDM4EHTT | |
| SCHEMBL24484900 | 0.89 | LMNA (0.42) | LMNAL3MBTL1MAPK1KDM4EHTT | |
| SCHEMBL29630214 | 0.85 | TSHR (0.40) | LMNAL3MBTL1MAPK1KDM4ETSHR | |
| SCHEMBL29096004 | 0.85 | TSHR (0.40) | LMNAL3MBTL1MAPK1KDM4ETSHR | |
| SCHEMBL29095709 | 0.82 | TSHR (0.49) | LMNAL3MBTL1MAPK1KDM4EHTT | |
| SCHEMBL30569429 | 0.80 | CASP3 (0.50) | LMNAL3MBTL1MAPK1KDM4EHTT | |
| SCHEMBL24470885 | 0.80 | CASP3 (0.50) | LMNAL3MBTL1MAPK1KDM4EHTT | |
| SCHEMBL24484858 | 0.80 | GABRA1 (0.32) | LMNAHTT | |
| SCHEMBL29629758 | 0.80 | GABRA1 (0.32) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |