Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2909153 | 0.98 | ALDH1A1 (0.48) | ALDH1A1ALDH2RARBKMT2AMEN1 | |
| SCHEMBL5654877 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL4811989 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALDH2RARBKMT2AMEN1 | |
| Bromide SCHEMBL3797608 | 0.75 | KDM4E (0.35) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL11570423 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ALDH2KMT2AMEN1MAPT | |
| SCHEMBL2912497 | 0.73 | FOLH1 (0.41) | ALDH1A1MAPTPOLBGAAHIF1A | |
| Hydrochloric Acid SCHEMBL2907706 | 0.72 | FOLH1 (0.41) | ALDH1A1MAPTPOLBGAAHIF1A | |
| SCHEMBL2912099 | 0.72 | LOXL2 (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL1063942 | 0.69 | ALDH1A1 (0.52) | ALDH1A1ALDH2KMT2AMEN1MAPT | |
| SCHEMBL3367595 | 0.69 | ALDH1A1 (0.63) | ALDH1A1RARBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507659-B2 | Method for chemically modifying biopolymer and polypeptide | FUJIFILM CORPORATION (JP) | 2013-08-13 | — | — | US | claimed |
| EP-2221334-B1 | METHOD FOR CHEMICALLY MODIFYING BIOPOLYMER AND POLYPEPTIDE | FUJIFILM CORP (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-8507659-B2 | Method for chemically modifying biopolymer and polypeptide | FUJIFILM CORPORATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20120315265-A1 | HYDROGEL-FORMING POLYMER, AND PREPARATION PROCESS AND USES THEREOF | CHANG GUNG UNIVERSITY (TW) | 2012-12-13 | — | — | US | disclosed |
| US-20100323421-A1 | METHOD FOR CHEMICALLY MODIFYING BIOPOLYMER AND POLYPEPTIDE | FUJIFILM CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2221334-A1 | METHOD FOR CHEMICALLY MODIFYING BIOPOLYMER OR POLYPEPTIDE | FUJIFILM Corporation (JP) | 2010-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120315265-A1 | HYDROGEL-FORMING POLYMER, AND PREPARATION PROCESS AND USES THEREOF | PDE6H, PDE6D, PDE6C | ALDH1A1 501/4885ALDH2 361/4885RARB 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.