Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654877 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL15514625 | 0.75 | CHRNB2 (0.36) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2909153 | 0.74 | ALDH1A1 (0.48) | KDM4EALDH1A1TDP1 | |
| SCHEMBL1079074 | 0.69 | — | — | |
| SCHEMBL4797252 | 0.66 | ALDH1A1 (0.68) | KDM4EALDH1A1TDP1 | |
| SCHEMBL5747742 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL4795693 | 0.64 | ALDH1A1 (0.74) | KDM4EALDH1A1TDP1 | |
| SCHEMBL13509798 | 0.64 | MGLL (0.44) | KDM4EALDH1A1TDP1 | |
| SCHEMBL12858954 | 0.62 | ALDH1A1 (0.56) | KDM4EALDH1A1TDP1 | |
| SCHEMBL1079287 | 0.62 | PHGDH (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659321-B2 | Photoinitiator anchored to silicate and use thereof to prepare polymer exfoliated silicate nanocomposite | CORNELL RESEARCH FOUNDATION, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20090018229-A1 | Nanocomposites prepared using nanoadditive containing dispersed silicate layers or inorganic nanoparticles | CORNELL RESEARCH FOUNDATION, INC. | 2009-01-15 | — | — | US | disclosed |
| US-20090012199-A1 | Photoinitiator anchored to silicate and use thereof to prepare polymer exfolidated silicate nanocomposite | NATIONAL SCIENCE FOUNDATION | 2009-01-08 | — | — | US | disclosed |
| WO-2006055373-A1 | NANOCOMPOSITES PREPARED USING NANOADDITVE CONTAINING DISPERSED SILICATE LAYERS OR INORGANIC NANOPARTICLES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006055372-A2 | PHOTOINITIATOR ANCHORED TO SILICATE AND USE THEREOF TO PREPARE POLYMER EXFOLIATED SILICATE NANOCOMPOSITE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012199-A1 | Photoinitiator anchored to silicate and use thereof to prepare polymer exfolidated silicate nanocomposite | MSN, NAPA, SELE | KDM4E 3352/4885ALDH1A1 3240/4885TDP1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.