Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403833 | 0.81 | MGLL (0.43) | ALDH1A1MGLLCES2CES1AKR1B1 | |
| Hydrochloric Acid SCHEMBL2909153 | 0.80 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAPOLBMAPT | |
| SCHEMBL2909293 | 0.80 | FOLH1 (0.46) | TP53 | |
| Bromide SCHEMBL3797608 | 0.78 | KDM4E (0.35) | ALDH1A1TDP1 | |
| SCHEMBL15514625 | 0.78 | CHRNB2 (0.36) | ALDH1A1 | |
| SCHEMBL2912497 | 0.76 | FOLH1 (0.41) | ALDH1A1LMNATP53POLBMAPT | |
| SCHEMBL2912099 | 0.75 | LOXL2 (0.40) | ALDH1A1LMNACA2TP53MAPT | |
| SCHEMBL9870759 | 0.74 | MGLL (0.47) | ALDH1A1MGLLCES2CES1AKR1B1 | |
| SCHEMBL1095539 | 0.73 | MAOA (0.40) | ALDH1A1MAPT | |
| SCHEMBL15124023 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265499-B1 | POLYMERIZING MIXTURE | MENICON CO., LTD. (JP) | 2001-07-24 | — | — | US | claimed |
| EP-1616957-B1 | VECTOR | NAT CEREBRAL & CARDIOVASCULAR CT (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-8298817-B2 | Vector | NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20060057714-A1 | Vector | JAPAN AS REPRESENTED BY PRESIDENT OF NATIONAL CARDIOVASCULAR CENTER | 2006-03-16 | — | — | US | disclosed |
| EP-1616957-A1 | VECTOR | Japan as represented by president of National Cardiovascular Center (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-5880232-A | FREE RADICAL POLYMERIZATION IN THE PRESENCE OF SULFIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5703184-A | SUSPENSION POLYMERIZATION; BATCH OR CONTINUOUS BULK POLYMERIZATION; DITHIOCARBAMATE OR OTHER SULFUR COMPOUND AS CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |