SCHEMBL29097233

SCHEMBL29097233

Cc1nn(C)c(Nc2ccc(Cl)cc2F)c1C1=C(Cl)CC(F)(F)C=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PROKR1 Q8TCW9 3/20 0.35
FPR2 P25090 2/20 0.35
BCDIN3D Q7Z5W3 1/20 0.33
KMT2A Q03164 2/20 0.33
TRPM5 Q9NZQ8 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
EGFR P00533 2/20 0.32
KDR P35968 2/20 0.31
PDGFRB P09619 1/20 0.31
MKNK1 Q9BUB5 1/20 0.31
MEN1 O00255 1/20 0.30
NUDT1 P36639 1/20 0.30
OPRM1 P35372 2/20 0.30
BRD4 O60885 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170661 0.72 EGFR (0.39) BCDIN3DKMT2ATRPM5CYP1A2CYP3A4
SCHEMBL170154 0.70 CYP1A2 (0.43) KMT2ACYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL17200649 0.64 HSD11B1 (0.38) CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL173314 0.63 GRM4 (0.39) KMT2ACYP1A2CYP2C9CYP2C19MEN1
SCHEMBL30308993 0.61 MAPK1 (0.44) BCDIN3DKMT2ACYP1A2CYP3A4CYP2C9
SCHEMBL171493 0.61 MAPK1 (0.44) BCDIN3DKMT2ACYP1A2CYP3A4CYP2C9
SCHEMBL9998142 0.61 ADORA1 (0.41) CYP1A2CYP3A4CYP2C9CYP2C19KDR
SCHEMBL14990088 0.61 CYP1A2 (0.42) CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL23804454 0.61 L3MBTL1 (0.41) KMT2AMEN1
SCHEMBL30211202 0.61 L3MBTL1 (0.41) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116801720-A Novel agrochemical compositions comprising 3-substituted benzamidine compounds and uses thereof 皮埃企业有限公司 2023-09-22 CN disclosed