Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29097359

COc1cc(C(=O)OCc2ccccc2)c(OCC(N)Cc2ccccc2)cn1.O=C(O)C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
AKT1 P31749 2/20 0.39
POLB P06746 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TACR1 P25103 1/20 0.37
OPRK1 P41145 2/20 0.37
RAB9A P51151 2/20 0.37
TSHR P16473 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
DHODH Q02127 1/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
MAPK10 P53779 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29828724 1.00 SCN4A (0.41) SCN4AL3MBTL1AKT1POLBMEN1
Trifluoroacetic Acid SCHEMBL27147895 0.89 SCN4A (0.44) SCN4AAKT1POLBMEN1KMT2A
SCHEMBL27032920 0.88 SCN4A (0.41) SCN4AAKT1POLBMEN1KMT2A
SCHEMBL30639503 0.84 SCN4A (0.49) SCN4AAKT1MEN1KMT2ATACR1
Trifluoroacetic Acid SCHEMBL30916083 0.74 LMNA (0.35) SCN4AAKT1MEN1KMT2AOPRK1
Trifluoroacetic Acid SCHEMBL29828782 0.74 LTA4H (0.40) SCN4AL3MBTL1AKT1MEN1KMT2A
Trifluoroacetic Acid SCHEMBL29097047 0.74 LTA4H (0.40) SCN4AL3MBTL1AKT1MEN1KMT2A
Trifluoroacetic Acid SCHEMBL30916049 0.73 DHODH (0.36) SCN4AAKT1OPRK1RAB9ADHODH
Hydrochloric Acid SCHEMBL29096940 0.72 SCN4A (0.45) SCN4AL3MBTL1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL29096944 0.72 SCN4A (0.45) SCN4AL3MBTL1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116981672-A Macrocyclic compounds as CFTR modulators 爱杜西亚药品有限公司 2023-10-31 CN disclosed