Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098107 | 1.00 | HDAC1 (0.48) | HDAC1HDAC6HDAC5HRH3PRMT5 | |
| SCHEMBL29097946 | 0.85 | PRMT5 (0.44) | HDAC1HDAC6HDAC5PRMT5EGFR | |
| SCHEMBL29097903 | 0.79 | DRD2 (0.47) | PRMT5EGFRPTGER1PNMTDRD2 | |
| SCHEMBL16518131 | 0.77 | PRCP (0.50) | HDAC1HDAC6HDAC5PNMTDRD2 | |
| SCHEMBL30199396 | 0.77 | DRD2 (0.57) | HRH3PRMT5EGFRPNMTDRD2 | |
| SCHEMBL30199135 | 0.77 | PNMT (0.44) | PRMT5EGFRPTGER1PNMTDRD2 | |
| SCHEMBL30199144 | 0.77 | DRD2 (0.57) | HRH3PRMT5EGFRPNMTDRD2 | |
| SCHEMBL29097839 | 0.77 | DRD2 (0.57) | HRH3PRMT5EGFRPNMTDRD2 | |
| SCHEMBL29098094 | 0.77 | PNMT (0.44) | PRMT5EGFRPTGER1PNMTDRD2 | |
| SCHEMBL29097955 | 0.77 | DRD2 (0.57) | HRH3PRMT5EGFRPNMTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |