Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9853476 | 0.96 | HDAC8 (0.35) | HDAC8TP53 | |
| Iodide SCHEMBL11385773 | 0.96 | HDAC8 (0.35) | HDAC8TP53 | |
| Iodide SCHEMBL11395802 | 0.81 | HDAC8 (0.33) | HDAC8 | |
| Bromide SCHEMBL6834383 | 0.78 | KCNH2 (0.41) | HDAC8 | |
| SCHEMBL6533529 | 0.78 | KCNH2 (0.49) | — | |
| Iodide SCHEMBL11381499 | 0.78 | KCNH2 (0.41) | HDAC8KDM4E | |
| SCHEMBL362206 | 0.78 | HDAC8 (0.32) | HDAC8 | |
| Hydrochloric Acid SCHEMBL5688232 | 0.77 | CALM1 (0.39) | TP53KDM4E | |
| SCHEMBL3661655 | 0.74 | CALM1 (0.41) | HDAC8TP53 | |
| Hydrochloric Acid SCHEMBL3479419 | 0.73 | KDM4E (0.46) | HDAC8TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605522-A | Coating composition, method for producing a hydrophilic coating on a substrate and medical device comprising such a coating | 帝斯曼知识产权资产管理有限公司（NL） | 2023-01-13 | — | — | CN | disclosed |