Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5688232

C=C[n+]1ccccc1Cc1ccccc1.[Cl-]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.39
KCNH2 Q12809 1/20 0.32
TP53 P04637 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
CYP2C9 P11712 1/20 0.32
MAOB P27338 1/20 0.31
LMNA P02545 3/20 0.31
TAAR1 Q96RJ0 2/20 0.31
BCL2 P10415 1/20 0.31
BCL2L1 Q07817 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSP90AA1 P07900 1/20 0.30
CYP1A2 P05177 1/20 0.30
ADRA2A P08913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3661655 0.98 CALM1 (0.41) CALM1KCNH2TP53APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL11136365 0.78 LMNA (0.36) CALM1LMNAKDM4EALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL31692825 0.77 RELA (0.46) APOBEC3AAPOBEC3GLMNAKDM4EMEN1
Hydrochloric Acid SCHEMBL29098366 0.77 HDAC8 (0.35) TP53KDM4E
Hydrochloric Acid SCHEMBL11139561 0.76 IGF1R (0.38) MAOBMEN1KMT2A
Hydrochloric Acid SCHEMBL17968398 0.75 KDM4E (0.41) CALM1KCNH2TP53APOBEC3AAPOBEC3G
SCHEMBL362206 0.75 HDAC8 (0.32)
Bromide SCHEMBL9853476 0.73 HDAC8 (0.35) TP53
Iodide SCHEMBL11385773 0.73 HDAC8 (0.35) TP53
SCHEMBL17968399 0.73 KDM4E (0.38) CALM1KCNH2TP53APOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4600687-A Photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-07-15 US claimed
US-4323644-A ACRYLIC COPOLYMER USEFUL AS A FIXATURE OR GELATIN HARDENING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1982-04-06 US claimed
EP-1367434-B1 Imaging element comprising solubilized collagen gelatin and hardener EASTMAN KODAK CO (US) 2006-04-26 EP disclosed
EP-1367436-A1 Coating fluid for imaging element comprising solubilized ossein gelatin and hardener EASTMAN KODAK COMPANY (US) 2003-12-03 EP disclosed
EP-1367434-A1 Imaging element comprising solubilized collagen gelatin and hardener EASTMAN KODAK COMPANY (US) 2003-12-03 EP disclosed
US-6589326-B1 By the hydrolysis of ossein using sodium or potassium hydroxide EASTMAN KODAK COMPANY 2003-07-08 US disclosed
US-6573037-B1 Wet mechanical strength EASTMAN KODAK COMPANY 2003-06-03 US disclosed
EP-0821267-B1 Hardening a hydrophilic colloid composition EASTMAN KODAK CO (US) 2001-11-14 EP disclosed
US-5958660-A PHOTOGRAPHIC ELEMENT COMPRISING A SUPPORT BEARING A LIGHT SENSITIVE LAYER AND ANOTHER LAYER COMPRISING A HYDROPHILIC COLLOID AND A WATER SOLUBLE POLYMER OF BORIC ACID, AND IN ONE LAYER A HARDENING AGENT FOR THE COLLOID; IMPROVED HARDENING EASTMAN KODAK COMPANY (US) 1999-09-28 US disclosed
EP-0927910-A1 Hydrophilic colloid composition EASTMAN KODAK COMPANY (US) 1999-07-07 EP disclosed
US-5914224-A CONSISTS OF ONE LIGHT SENSITIVE SILVER HALIDE EMULSION LAYER AND ONE NON-LIGHT SENSITIVE LAYER ON A SUPPORT; A HARDENER SELECTED FROM VINYL SULFONE HARDENER, CARBOXY ACTIVATING HARDENER AND POLYMERIC HARDENER KONICA CORPORATION (JP) 1999-06-22 US disclosed
US-4481284-A PREVENTION OF RETICULATION AND SCUM FUJI PHOTO FILM CO., LTD. (JP) 1984-11-06 US disclosed
US-4476218-A LONGER MELTING LAYER OF NONDIFFUSING POLMER-= BASED GELATIN; ANTISOILANTS; AUTOMATIC DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 1984-10-09 US disclosed
EP-0119761-A2 Process for preparing silver halide photographic light-sensitive material for photo-mechanical process FUJI PHOTO FILM CO., LTD. (JP) 1984-09-26 EP disclosed
EP-0114699-A2 Silver halide photographic material for photomechanical process and method for reduction processing the same FUJI PHOTO FILM CO., LTD. (JP) 1984-08-01 EP disclosed
US-4460680-A GELATIN LAYER HARDENED WITH POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1984-07-17 US disclosed
US-4397943-A POLYMERIC 1,2,4-TRIAZOLO-1,5-A-PYRIMIDINES AS STABILIZERS FUJI PHOTO FILM CO., LTD. (JP) 1983-08-09 US disclosed
US-4323644-A ACRYLIC COPOLYMER USEFUL AS A FIXATURE OR GELATIN HARDENING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1982-04-06 US disclosed
US-4225407-A REDUCIBLE NITROGEN-CONTAINING CATIONS THE DOW CHEMICAL COMPANY (US) 1980-09-30 US disclosed
US-4080346-A DIFFUSION TRANSFER IMAGE DYE MORDANTS POLAROID CORPORATION (US) 1978-03-21 US disclosed