Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | CBS | P35520 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887066 | 0.97 | PAM (0.39) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL18232156 | 0.91 | PAM (0.44) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL41709 | 0.81 | TP53 (0.43) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL27483337 | 0.81 | TP53 (0.43) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL7810255 | 0.80 | NPC1 (0.38) | TSHRALDH1A1NPC1MEN1LMNA | |
| SCHEMBL7120017 | 0.79 | TP53 (0.41) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL21582138 | 0.79 | TSHR (0.42) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL15008849 | 0.79 | TP53 (0.41) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL9305155 | 0.79 | PAM (0.38) | PAMTSHRCTHCBSTHPO | |
| SCHEMBL25946615 | 0.79 | PAM (0.38) | PAMTSHRCTHCBSTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118726541-A | Oligonucleotide fluorescent probe and method for detecting environmental DNA by using same | 青岛聚点儿科技有限公司 | 2024-10-01 | — | — | CN | claimed |
| US-20150021528-A1 | SOLUBLE FUNCTIONALIZED NANOPARTICLES FOR USE IN OPTICAL MATERIALS | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF UNIVERSITY (US) | 2015-01-22 | — | — | US | claimed |
| CN-118726541-A | Oligonucleotide fluorescent probe and method for detecting environmental DNA by using same | 青岛聚点儿科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| US-20230058729-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2023-02-23 | — | — | US | disclosed |
| US-11136327-B2 | Macrocycles as factor XIA inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-10-05 | — | — | US | disclosed |
| US-20180022753-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-01-25 | — | — | US | disclosed |
| US-9802939-B2 | Macrocycles as factor XIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-10-31 | — | — | US | disclosed |
| US-9513406-B2 | Soluble functionalized nanoparticles for use in optical materials | UNIVERSITY OF OREGON (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160147150-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20160147150-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20150112058-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-04-23 | — | — | US | disclosed |
| US-20120041190-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-02-16 | — | — | US | disclosed |
| EP-1492759-B1 | NOVEL ALICYCLIC ESTERS HAVING A MUSKY SMELL | SYMRISE GMBH & CO KG (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-7064102-B2 | Alicyclic esters having a musky smell | SYMRISE GMBH & CO, KG (DE) | 2006-06-20 | — | — | US | disclosed |
| US-20050182273-A1 | Novel alicyclic esters having a musky smell | SYMRISE AG (DE) | 2005-08-18 | — | — | US | disclosed |
| CN-1653142-A | Coating composition comprising an acetal-functional binder | AKZO NOBEL COATINGS INT BV (NL) | 2005-08-10 | — | — | CN | disclosed |
| EP-1492759-A2 | NOVEL ALICYCLIC ESTERS HAVING A MUSKY SMELL | Symrise GmbH & Co. KG (DE) | 2005-01-05 | — | — | EP | disclosed |
| CN-1478092-A | Benzoxazinone derivatives, their preparation and use | ʷ | 2004-02-25 | — | — | CN | disclosed |
| WO-2003082799-A2 | ALICYCLIC ESTERS HAVING A MUSKY SMELL | SYMRISE GMBH & CO. KG (DE) | 2003-10-09 | — | — | WO | disclosed |
| US-5705680-A | Process for the preparation of O-acylglycolanilides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150112058-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | PAM 2965/4885TSHR 2404/4885CTH 2307/4885 |
| US-20120041190-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | PAM 2965/4885TSHR 2404/4885CTH 2307/4885 |
| US-20050182273-A1 | Novel alicyclic esters having a musky smell | TAS2R16, TAS2R43, TAS2R45 | PAM 2506/4885TSHR 4747/4885CTH 2898/4885 |
| US-11136327-B2 | Macrocycles as factor XIA inhibitors | TFPI, TFPI2, F11 | PAM 2965/4885TSHR 2404/4885CTH 2307/4885 |
| US-20180022753-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | PAM 2965/4885TSHR 2404/4885CTH 2307/4885 |
| US-20230058729-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | PAM 2965/4885TSHR 2404/4885CTH 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.