Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.34 |
| ▸ | GSK3B | P49841 | 7/20 | 0.34 |
| ▸ | CLK2 | P49760 | 3/20 | 0.34 |
| ▸ | CLK3 | P49761 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099890 | 1.00 | TLR8 (0.34) | TLR8DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL30623094 | 0.93 | TLR8 (0.40) | TLR8DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL29093590 | 0.81 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL29093593 | 0.81 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL30623078 | 0.79 | TLR8 (0.55) | TLR8HRH4TLR7 | |
| SCHEMBL30557848 | 0.76 | TLR8 (0.45) | TLR8DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL29093600 | 0.74 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29093607 | 0.74 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29093582 | 0.73 | TLR8 (0.61) | TLR8TLR7 | |
| SCHEMBL29099899 | 0.72 | AURKB (0.36) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969934-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-10-31 | — | — | CN | disclosed |