Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.34 |
| ▸ | CLK3 | P49761 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099892 | 0.93 | TLR8 (0.34) | TLR8TLR7DYRK1AGSK3BCLK2 | |
| SCHEMBL29099890 | 0.93 | TLR8 (0.34) | TLR8TLR7DYRK1AGSK3BCLK2 | |
| SCHEMBL30623078 | 0.87 | TLR8 (0.55) | TLR8TLR7GAKAXLMERTK | |
| SCHEMBL30557848 | 0.84 | TLR8 (0.45) | TLR8TLR7DYRK1AGSK3BCLK2 | |
| SCHEMBL29093600 | 0.80 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29093607 | 0.80 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29093582 | 0.77 | TLR8 (0.61) | TLR8TLR7 | |
| SCHEMBL29093590 | 0.75 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL29093593 | 0.75 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL30623092 | 0.75 | TLR8 (0.49) | TLR8TLR7AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969934-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-10-31 | — | — | CN | disclosed |