Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151055 | 0.84 | CYP1A2 (0.40) | TSHRLMNARECQLMAPTTHRB | |
| SCHEMBL29100173 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAGRIN2DGRIN3B | |
| SCHEMBL29100216 | 0.78 | ATM (0.51) | ALDH1A1TSHRLMNARECQLMAPT | |
| SCHEMBL29902863 | 0.78 | LMNA (0.42) | ALDH1A1LMNARECQLMAPTTHRB | |
| SCHEMBL309614 | 0.77 | TSHR (0.38) | ALDH1A1TSHRMAPTGRIN2DGRIN3B | |
| SCHEMBL31414230 | 0.77 | CES2 (0.44) | ALDH1A1 | |
| SCHEMBL25368848 | 0.76 | LMNA (0.45) | ALDH1A1LMNAMAPTTHRBMEN1 | |
| SCHEMBL11669893 | 0.76 | CYP3A4 (0.47) | ALDH1A1TSHRLMNAMAPTMEN1 | |
| SCHEMBL1151404 | 0.76 | TSHR (0.50) | ALDH1A1TSHRLMNAMAPTGRIN2D | |
| SCHEMBL7252708 | 0.75 | LMNA (0.52) | ALDH1A1TSHRLMNARECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116808229-A | Polyethylene glycol-nemaltevir prodrug as well as preparation method and application thereof | 长沙创新药物工业技术研究院有限公司 | 2023-09-29 | — | — | CN | disclosed |