Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PCNA | P12004 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29902904 | 0.91 | LMNA (0.39) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL29902848 | 0.80 | LMNA (0.52) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL1151055 | 0.80 | CYP1A2 (0.40) | LMNARECQLTHRBMAPTTDP1 | |
| SCHEMBL29100178 | 0.78 | ALDH1A1 (0.34) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL25368848 | 0.75 | LMNA (0.45) | LMNAALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL1151448 | 0.74 | MTNR1A (0.43) | LMNAALDH1A1THRBMAPTL3MBTL1 | |
| SCHEMBL13329774 | 0.73 | KMT2A (0.53) | LMNAALDH1A1MEN1KMT2APCNA | |
| SCHEMBL12693888 | 0.73 | POLB (0.38) | ALDH1A1MAPTTDP1POLB | |
| SCHEMBL309614 | 0.73 | TSHR (0.38) | ALDH1A1MAPTTDP1POLB | |
| SCHEMBL7437807 | 0.73 | HSP90AB1 (0.49) | LMNARECQLALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077316-A1 | BENZIMIDAZOLE DERIVATIVES | Pfizer Inc. (US) | 2022-10-26 | — | — | EP | disclosed |