SCHEMBL29100201

SCHEMBL29100201

O=Cc1ccccc1-c1cc(O)ccc1Br

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP26A1 O43174 1/20 0.40
ERN1 O75460 5/20 0.38
CHRNA7 P36544 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
TYR P14679 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
LCK P06239 1/20 0.35
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16050103 0.86 PTPRC (0.48) TRIM24TRIM33MEN1LMNATHRB
SCHEMBL3062652 0.85 TRIM24 (0.48) TRIM24TRIM33MEN1LMNATHRB
SCHEMBL28664936 0.82 TRIM24 (0.50) TRIM24TRIM33MEN1LMNATHRB
SCHEMBL1979357 0.80 TRIM24 (0.52) TRIM24TRIM33MEN1LMNATHRB
SCHEMBL31588291 0.79 LMNA (0.52) TRIM24TRIM33MEN1LMNATHRB
SCHEMBL1984908 0.79 LMNA (0.52) TRIM24TRIM33MEN1LMNATHRB
SCHEMBL9440083 0.77 ESR1 (0.46) MEN1LMNABLMKMT2AALDH1A1
SCHEMBL1958671 0.76 PTGS2 (0.40) MEN1LMNAKMT2ACYP26A1ERN1
SCHEMBL289452 0.75 BACE1 (0.49) TRIM24TRIM33MEN1LMNAKMT2A
SCHEMBL31302309 0.75 BACE1 (0.49) TRIM24TRIM33MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947946-B Kidney-clearing type double-channel optical nano probe and preparation method and application thereof 中山大学 2023-11-07 CN disclosed