An-9

An-9

SCHEMBL29100445

CCCC(=O)OCOC(=O)C(C)(C)C.[NaH]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
DGKA P23743 1/20 0.36
PRKCA P17252 1/20 0.36
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
BTN3A1 O00481 4/20 0.34
PAM P19021 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
ELANE P08246 3/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.32
FFAR3 O14843 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
An-9 SCHEMBL356482 0.98 ALDH1A1 (0.46) ALDH1A1DGKAPRKCAPOLBGAA
Bis(Pivaloyloxymethyl) Succinate SCHEMBL3123390 0.87 PRKCA (0.41) ALDH1A1DGKAPRKCAPOLBGAA
SCHEMBL5539605 0.86 DGKA (0.48) ALDH1A1DGKAPRKCAPAMCES2
SCHEMBL4705395 0.83 DGKA (0.50) ALDH1A1DGKAPRKCAPOLBGAA
SCHEMBL3835100 0.83 DGKA (0.43) ALDH1A1DGKAPRKCABTN3A1PAM
SCHEMBL25635496 0.82 DGKA (0.60) ALDH1A1DGKAPRKCAPAMELANE
SCHEMBL681950 0.82 PRKCA (0.46) ALDH1A1PRKCAPOLBGAANPSR1
SCHEMBL2618716 0.82 ALDH1A1 (0.63) ALDH1A1DGKAGAAPAMCES2
SCHEMBL2625610 0.82 ALDH1A1 (0.48) ALDH1A1DGKAPAMCES2CES1
SCHEMBL18350229 0.82 ALDH1A1 (0.43) ALDH1A1DGKAPRKCAPAMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116782949-A Use of short chain fatty acids in cancer prevention 英联邦高等教育系统天普大学 2023-09-19 CN disclosed