SCHEMBL29100772

SCHEMBL29100772

CC(C)(C)c1cccnc1OC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 17/20 0.44
P2RY14 Q15391 2/20 0.41
PLCG1 P19174 1/20 0.39
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2635568 0.83 KIF11 (0.42) P2RY1
Hydrochloric Acid SCHEMBL26136590 0.82 TRPV1 (0.41) P2RY1
SCHEMBL29136750 0.81 ALDH1A1 (0.47) P2RY1P2RY14PLCG1
SCHEMBL28683997 0.77 PLAU (0.44) RAB9A
SCHEMBL1767096 0.75 RAB9A (0.41) RAB9A
SCHEMBL5206688 0.75 RAB9A (0.41) RAB9A
SCHEMBL7605126 0.75 KDM4E (0.41) RAB9A
SCHEMBL29057636 0.75 MKNK1 (0.40) P2RY1
SCHEMBL28453579 0.75 RAB9A (0.44) RAB9A
SCHEMBL16737211 0.75 SLC13A5 (0.41) P2RY1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111630051-B Olefin spiro compounds as farnesol X receptor modulators 百时美施贵宝公司 2023-12-26 CN disclosed
CN-117120442-A Tricyclic compounds useful for treating cancer, autoimmune disorders, and inflammatory disorders 薛定谔公司 2023-11-24 CN disclosed
CN-116981667-A Heterocyclic inhibitors of EGFR and/or HER2 for cancer treatment 蝎子疗法股份有限公司 2023-10-31 CN disclosed
CN-116802181-A Triazolopyridine compounds as kinase inhibitors 百时美施贵宝公司 2023-09-22 CN disclosed
CN-111511731-B Olefin compounds as modulators of the farnesol X receptor 百时美施贵宝公司 2023-05-23 CN disclosed