Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548916 | 0.78 | GPR119 (0.33) | ESR2GPR119GRM5NR1H2ELANE | |
| SCHEMBL28449477 | 0.77 | USP2 (0.36) | ESR2GPR119GRM5USP2SMN1; SMN2 | |
| SCHEMBL28686795 | 0.74 | ESR2 (0.34) | ESR2GPR119GRM5USP2SMN1; SMN2 | |
| SCHEMBL17481737 | 0.72 | USP2 (0.41) | ESR2GPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL2980997 | 0.72 | ESR2 (0.43) | ESR2GPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL29100854 | 0.70 | GPR119 (0.38) | ESR2GPR119GRM5USP2SMN1; SMN2 | |
| SCHEMBL28696148 | 0.70 | NR1H2 (0.38) | ESR2GPR119GRM5USP2SMN1; SMN2 | |
| SCHEMBL20690515 | 0.70 | ALDH1A1 (0.40) | ESR2GPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL17942084 | 0.69 | GPR119 (0.39) | ESR2GPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL17942066 | 0.68 | USP2 (0.41) | ESR2GPR119USP2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997549-A | Pyrrolo [3,2-C ] pyridin-4-one derivatives for the treatment of cancer | 蝎子疗法股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116981667-A | Heterocyclic inhibitors of EGFR and/or HER2 for cancer treatment | 蝎子疗法股份有限公司 | 2023-10-31 | — | — | CN | disclosed |