Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29100 | 1.00 | MEN1 (0.45) | MEN1KMT2ANPC1PPARGPPARA | |
| SCHEMBL502 | 0.82 | TSHR (0.52) | KMT2ANPC1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL8881644 | 0.82 | TSHR (0.52) | KMT2ANPC1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL6510845 | 0.81 | PTGS2 (0.46) | NPC1PPARAPPARDMAPTRAB9A | |
| SCHEMBL1456261 | 0.81 | PTGS2 (0.46) | NPC1PPARAPPARDMAPTRAB9A | |
| SCHEMBL7617607 | 0.80 | TSHR (0.50) | KMT2ANPC1PPARGALDH1A1RAB9A | |
| SCHEMBL131471 | 0.79 | IDO1 (0.55) | NPC1RAB9AHTTTSHRLMNA | |
| SCHEMBL27597789 | 0.78 | TSHR (0.48) | KMT2ANPC1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL2920835 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2ANPC1ALDH1A1TRPA1 | |
| Cyanide SCHEMBL27392144 | 0.76 | TSHR (0.46) | MEN1KMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 837 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| EP-0695750-B1 | Naphthyridinium derivative, method for its production; antibody against said derivative and the use of said antibody | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2000-03-01 | — | — | EP | claimed |
| EP-0362941-B1 | 4-Methyl and 4-ethyl substituted pyrrolidin-2-ones | MERCK SHARP & DOHME (GB) | 1995-12-20 | — | — | EP | claimed |
| EP-0389437-B1 | Luciferin derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1995-05-24 | — | — | EP | claimed |
| EP-0220923-B1 | Dipeptides and process | GRACE W R & CO (US) | 1994-04-27 | — | — | EP | claimed |
| US-5128069-A | Luciferin derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1992-07-07 | — | — | US | claimed |
| US-5120746-A | Inhibit gastric acid secretion | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | claimed |
| US-4810817-A | ARTIFICIAL SWEETENERS | W. R. GRACE & CO. (US) | 1989-03-07 | — | — | US | claimed |
| US-4767863-A | Isoxazoline intermediates | BRISTOL-MYERS COMPANY (US) | 1988-08-30 | — | — | US | claimed |
| US-4710583-A | ENZYMATIC COUPLING OF PHENYLSERINE WITH ASPARTIC ACID; HYDROGENATION | W. R. GRACE & CO. (US) | 1987-12-01 | — | — | US | claimed |
| EP-0220923-A2 | Dipeptides and process | W.R. Grace & Co.-Conn. (US) | 1987-05-06 | — | — | EP | claimed |
| US-4643849-A | ANTIULCER, ANTISECRETORY AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-02-17 | — | — | US | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| EP-0011283-A1 | New lactyl tetrapeptide, processes for preparation thereof and pharmaceutical compositions containing it | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-28 | — | — | EP | claimed |
| US-4176009-A | HYDROLYZING OLIGOPEPTIDES IN A AQUEOUS SOLUTION TO RELEASE PEPTIDE FRAGMENTS, USING COLORIMETRIC ANALYSIS AFTER SOLVENT EXTRACTION | AJINOMOTO CO., INC. (JP) | 1979-11-27 | — | — | US | claimed |
| US-4138394-A | Peptide derivatives and a method of measuring collagenase activity | AJINOMOTO CO., INC. (JP) | 1979-02-06 | — | — | US | claimed |
| US-4086136-A | Process for producing a peptide using a serine or thiol proteinase | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1978-04-25 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | claimed |