Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HBB | P68871 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549408 | 0.85 | MEN1 (0.43) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7531320 | 0.80 | KMT2A (0.43) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL29100 | 0.77 | MEN1 (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL29101 | 0.77 | MEN1 (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL24815612 | 0.74 | ALDH1A1 (0.50) | ALDH1A1IDEMEN1KMT2AMAPT | |
| SCHEMBL15261382 | 0.74 | ALDH1A1 (0.50) | ALDH1A1IDEMEN1KMT2AMAPT | |
| SCHEMBL286872 | 0.74 | IDE (0.43) | ALDH1A1IDEMEN1KMT2AMAPT | |
| SCHEMBL16287599 | 0.73 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL21524964 | 0.71 | ALDH1A1 (0.50) | ALDH1A1IDEMEN1KMT2AMAPT | |
| SCHEMBL17923160 | 0.71 | ALDH1A1 (0.50) | ALDH1A1IDEMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667060-B1 | Prevents dose-dumping from hydrophilic formulation along gastrointestinal tract both in fasted as well as in fed conditions | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-12-23 | — | — | US | claimed |
| WO-2023231777-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023078398-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021065898-A1 | AZEPAN DERIVATIVE | 日本ケミファ株式会社 | 2021-04-08 | — | — | WO | disclosed |
| WO-2021047584-A1 | SUBSTITUTED (2-AZABICYCLO [3.1.0] HEXAN-2-YL) PYRAZOLO [1, 5-a] PYRIMIDINE AND IMIDAZO [1, 2-b] PYRIDAZINE COMPOUNDS AS TRK KINASES INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-03-18 | — | — | WO | disclosed |
| EP-3774812-A1 | MACROCYCLIC COMPOUNDS AS TRK KINASES INHIBITORS | Fochon Pharmaceuticals, Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| EP-3768661-A1 | DEUTERATED COMPOUNDS AS ROCK INHIBITORS | Fochon Pharmaceuticals, Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |
| EP-3765462-A1 | SUBSTITUTED (2-AZABICYCLO [3.1.0] HEXAN-2-YL) PYRAZOLO [1, 5-A] PYRIMIDINE AND IMIDAZO [1, 2-B] PYRIDAZINE COMPOUNDS AS TRK KINASES INHIBITORS | Fochon Pharmaceuticals, Ltd. (CN) | 2021-01-20 | — | — | EP | disclosed |
| EP-3612531-A1 | APOPTOSIS-INDUCING AGENTS | Shanghai Fochon Pharmaceutical Co., Ltd. (CN) | 2020-02-26 | — | — | EP | disclosed |
| EP-3565815-A1 | COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS | Shanghai Fochon Pharmaceutical Co., Ltd. (CN) | 2019-11-13 | — | — | EP | disclosed |
| WO-1992010511-A1 | COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | THE UNIVERSITY OF MELBOURNE (AU) | 1992-06-25 | — | — | WO | disclosed |
| EP-0414289-A1 | Spirocyclic antipsychotic agents | MERCK SHARP & DOHME LTD. (GB) | 1991-02-27 | — | — | EP | disclosed |
| EP-0410535-A2 | Octahydrobenzisoquinoline derivatives as antipsychotic agents | MERCK SHARP & DOHME LTD. (GB) | 1991-01-30 | — | — | EP | disclosed |
| EP-0380362-A1 | Biosynthetic uses of thermostable proteases | GENEX CORPORATION (a Delaware corporation) (US) | 1990-08-01 | — | — | EP | disclosed |
| EP-0362941-A2 | 4-Methyl and 4-ethyl substituted pyrrolidin-2-ones | MERCK SHARP & DOHME LTD. (GB) | 1990-04-11 | — | — | EP | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0034567-B1 | A METHOD FOR THE TOTAL SYNTHESIS OF CYCLOSPORINS AND NOVEL CYCLOSPORINS | SANDOZ AG (CH) | 1984-11-07 | — | — | EP | disclosed |
| EP-0043247-B1 | PEPTIDES FOR USE IN DETERMINING SERUM THYMIC FACTOR | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-02-01 | — | — | EP | disclosed |
| US-4404133-A | TYROSINE DERIVATIVES, SERUM THYMIC FACTOR ANALOGS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0043247-A1 | Peptides for use in determining serum thymic factor | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-01-06 | — | — | EP | disclosed |