Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.78 |
| ▸ | HTR2A | P28223 | 6/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.63 |
| ▸ | SCN1A | P35498 | 3/20 | 0.63 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | THPO | P40225 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802493 | 0.88 | HRH1 (1.00) | HRH1HTR2ASLC6A2SLC6A4CHRM2 | |
| Hydrochloric Acid SCHEMBL11383046 | 0.86 | HRH1 (0.95) | HRH1HTR2ASLC6A2SLC6A4CHRM2 | |
| Tolpropamine SCHEMBL1651656 | 0.80 | HRH1 (0.75) | HRH1HTR2ASLC6A2SLC6A4CHRM2 | |
| Tolpropamine SCHEMBL29300 | 0.79 | HRH1 (0.81) | HRH1HTR2ASLC6A2SLC6A4CHRM2 | |
| SCHEMBL29173261 | 0.79 | SLC6A2 (0.57) | HRH1HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL123538 | 0.78 | SLC6A3 (0.61) | HRH1HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10778672 | 0.78 | HTR2A (0.78) | HRH1HTR2ASLC6A2SLC6A4CHRM2 | |
| Tolpropamine SCHEMBL4193587 | 0.78 | HRH1 (0.78) | HRH1HTR2ASLC6A2SLC6A4CHRM2 | |
| Pheniramine SCHEMBL126153 | 0.77 | CHRM2 (1.00) | HRH1HTR2ASLC6A2SLC6A4CHRM2 | |
| Pheniramine SCHEMBL4796 | 0.77 | CHRM2 (1.00) | HRH1HTR2ASLC6A2SLC6A4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003787-A | Selective silicon-based-arylation method of olefin compound | 南京大学 | 2023-11-07 | — | — | CN | disclosed |