SCHEMBL29173261

SCHEMBL29173261

CCCC(c1ccccc1)c1ccncc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.57
SLC6A4 P31645 2/20 0.57
SLC6A3 Q01959 2/20 0.57
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
MAPT P10636 1/20 0.54
EPHX2 P34913 1/20 0.47
HRH1 P35367 5/20 0.45
HTR2A P28223 4/20 0.45
S1PR1 P21453 1/20 0.45
CYP19A1 P11511 2/20 0.44
SIGMAR1 Q99720 1/20 0.44
GAA P10253 1/20 0.44
CCR2 P41597 1/20 0.43
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107889 0.87 HRH1 (0.56) SLC6A2SLC6A4SLC6A3ALDH1A1HRH1
Hydrochloric Acid SCHEMBL6521685 0.84 HRH1 (0.54) SLC6A2SLC6A4SLC6A3ALDH1A1HRH1
SCHEMBL28229621 0.84 HRH1 (0.54) SLC6A2SLC6A4SLC6A3ALDH1A1HRH1
Ammonia Solution, Strong SCHEMBL5724927 0.84 HRH1 (0.54) SLC6A2SLC6A4SLC6A3ALDH1A1HRH1
Hydrogen Peroxide SCHEMBL27864054 0.84 HRH1 (0.54) SLC6A2SLC6A4SLC6A3ALDH1A1EPHX2
SCHEMBL123538 0.83 SLC6A3 (0.61) SLC6A2SLC6A4SLC6A3ALDH1A1POLB
SCHEMBL23970158 0.82 TBXAS1 (0.56) SLC6A2SLC6A4SLC6A3EPHX2LMNA
SCHEMBL13127487 0.82 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3ALDH1A1POLB
Ethylene SCHEMBL28169737 0.82 HRH1 (0.52) SLC6A2SLC6A4SLC6A3ALDH1A1HRH1
SCHEMBL12190347 0.81 ALDH1A1 (0.53) SLC6A2SLC6A4SLC6A3ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117702142-A C (C) 4 Process for preparing substituted pyridine derivatives 五邑大学 2024-03-15 CN disclosed