SCHEMBL29102004

SCHEMBL29102004

O=C(OCCC=Cc1cccc(Br)c1)OCCC=Cc1cccc(Br)c1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.53
PKM P14618 1/20 0.51
SLC6A19 Q695T7 1/20 0.47
BACE1 P56817 1/20 0.47
MAOB P27338 3/20 0.44
MAOA P21397 2/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP2D6 P10635 1/20 0.43
CYP1B1 Q16678 1/20 0.43
HTT P42858 2/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28849828 0.82 ALOX5 (0.44) MAOBMAOAALDH1A1MEN1KMT2A
SCHEMBL29102005 0.81 GRIK1 (0.43) MAOBMAOAALDH1A1CYP2D6CYP1B1
SCHEMBL7112583 0.80 NAAA (0.53) MAOBALDH1A1CYP2D6MAPT
SCHEMBL2807250 0.80 HSD17B3 (0.45) HSD17B3PKMSLC6A19BACE1MAOB
SCHEMBL2807247 0.80 HSD17B3 (0.45) HSD17B3PKMSLC6A19BACE1MAOB
SCHEMBL571592 0.78 HSD17B3 (0.56) HSD17B3PKMSLC6A19BACE1MAOB
SCHEMBL21791369 0.78 HSD17B3 (0.56) HSD17B3PKMSLC6A19BACE1MAOB
SCHEMBL571591 0.78 HSD17B3 (0.56) HSD17B3PKMSLC6A19BACE1MAOB
SCHEMBL933470 0.77 HSD17B3 (0.53) HSD17B3PKMSLC6A19BACE1MAOB
SCHEMBL28849822 0.77 HSD17B3 (0.54) HSD17B3PKMSLC6A19BACE1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736108-B Allyl carbonyl enol compound and synthesis method thereof 同济大学 2023-10-27 CN disclosed