SCHEMBL29102005

SCHEMBL29102005

O=C(OCCC=Cc1ccc(Br)cc1)OCCC=Cc1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.43
GRIK2 Q13002 1/20 0.43
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MEN1 O00255 2/20 0.41
MAPK1 P28482 2/20 0.41
KMT2A Q03164 2/20 0.41
S1PR4 O95977 1/20 0.41
S1PR1 P21453 1/20 0.41
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NAAA Q02083 2/20 0.39
MAOB P27338 2/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28462212 0.82 GRIK1 (0.45) GRIK1GRIK2LMNAMAPTNPSR1
SCHEMBL7112583 0.82 NAAA (0.53) LMNAMAPTCYP1A2ALDH1A1CYP2C9
SCHEMBL29102004 0.81 HSD17B3 (0.53) MAPTNPSR1MEN1KMT2AALDH1A1
SCHEMBL28456636 0.80 GSK3B (0.54) GRIK1GRIK2LMNACYP1A2ALDH1A1
SCHEMBL16685853 0.77 TUBB4A (0.43) GRIK1GRIK2MAPTMEN1KMT2A
SCHEMBL16685855 0.77 TUBB4A (0.43) GRIK1GRIK2MAPTMEN1KMT2A
SCHEMBL29102006 0.76 TUBB1 (0.42) LMNAMAPTKMT2AS1PR1ALDH1A1
SCHEMBL19582800 0.75 GRIK1 (0.49) GRIK1GRIK2MAPTKMT2AALDH1A1
SCHEMBL5879286 0.74 GRIK1 (0.44) GRIK1GRIK2LMNAMAPTMEN1
SCHEMBL28462213 0.74 GRIK1 (0.48) GRIK1GRIK2LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736108-B Allyl carbonyl enol compound and synthesis method thereof 同济大学 2023-10-27 CN disclosed