SCHEMBL29102410

SCHEMBL29102410

Oc1ccccc1C#Cc1ccncc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.49
PIK3CA P42336 3/20 0.41
MTOR P42345 3/20 0.41
PIK3CD O00329 1/20 0.41
PIK3CG P48736 1/20 0.41
PDK1 Q15118 1/20 0.41
GRM5 P41594 3/20 0.41
NPC1 O15118 3/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673209 0.83 FFAR1 (0.59) FFAR1PIK3CAMTORGRM5NPC1
SCHEMBL15688668 0.80 ALDH1A1 (0.53) FFAR1PIK3CAMTORNPC1KDM4E
SCHEMBL28933420 0.76 CA12 (0.57) FFAR1GRM5NPC1KDM4EALDH1A1
SCHEMBL28933437 0.76 FFAR1 (0.53) FFAR1PIK3CAMTORGRM5NPC1
SCHEMBL28933373 0.76 FFAR1 (0.53) FFAR1NPC1KDM4EALDH1A1CYP3A4
SCHEMBL2925968 0.75 APP (0.67) FFAR1PIK3CAMTORPIK3CDPIK3CG
SCHEMBL1820120 0.75 HDAC8 (0.58) FFAR1PIK3CAMTORPIK3CDPIK3CG
Acetic Acid SCHEMBL28454105 0.74 FFAR1 (0.59) FFAR1MTORNPC1KDM4EALDH1A1
SCHEMBL17224548 0.73 APP (0.63) FFAR1PIK3CAMTORPIK3CDPIK3CG
Methyl Alcohol SCHEMBL28280712 0.73 GRM5 (0.52) FFAR1PIK3CAMTORPIK3CDPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024759-A Organic Pt metal macrocyclic group two-dimensional supermolecule assembly constructed based on oriented cation-pi action, and preparation method and application thereof 陕西中医药大学 2023-11-10 CN disclosed