Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783342 | 0.78 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL2539312 | 0.64 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL23502011 | 0.63 | KIF11 (0.53) | KDM4ELMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15873533 | 0.62 | ACHE (0.55) | KDM4ELMNAMEN1KMT2AMAPK1 | |
| SCHEMBL25498024 | 0.60 | SIRT1 (0.55) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL713777 | 0.60 | HDAC8 (0.44) | KDM4ENR3C1NR3C2MEN1KMT2A | |
| SCHEMBL11827114 | 0.59 | KIF11 (0.45) | KDM4ELMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13797487 | 0.59 | AKR1B1 (0.44) | CCR2PKMALDH1A1PTGS2TRPV4 | |
| SCHEMBL26511201 | 0.59 | KIF11 (0.64) | KDM4ELMNAMEN1KMT2AMAPK1 | |
| SCHEMBL6004999 | 0.59 | PTGDR2 (0.39) | KDM4EPTGDR2LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219645-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | Oxagen Limited (GB) | 2010-08-25 | — | — | EP | claimed |
| WO-2009063215-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | OXAGEN LIMITED (GB) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063202-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | OXAGEN LIMITED (GB) | 2009-05-22 | — | — | WO | claimed |
| EP-2219645-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | Oxagen Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063202-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | OXAGEN LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |