Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277439 | 0.87 | LMNA (0.74) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL11552476 | 0.79 | TDP1 (0.62) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL30354928 | 0.79 | TDP1 (0.62) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL77208 | 0.79 | TDP1 (0.62) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL554299 | 0.78 | ALDH1A1 (0.75) | ALDH1A1HTTMAPTRAB9ANPSR1 | |
| SCHEMBL7173350 | 0.78 | HSPB1 (0.66) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL4477206 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL1486129 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL4033756 | 0.73 | MEN1 (0.62) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL30879375 | 0.73 | MEN1 (0.62) | ALDH1A1LMNAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |