SCHEMBL29105484

SCHEMBL29105484

O=P(O)(O)Oc1c(O)ccc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
INPPL1 O15357 5/20 0.46
INPP5A Q14642 4/20 0.46
AKT1 P31749 1/20 0.46
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 2/20 0.43
INPP5B P32019 1/20 0.43
TTR P02766 2/20 0.43
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
PDE3A Q14432 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
PNLIP P16233 1/20 0.36
CTNNB1 P35222 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL982234 0.83 TTR (0.50) KDM4EHSD17B10TTRALDH1A1HPGD
SCHEMBL28655315 0.79 INPPL1 (0.61) SRCINPPL1INPP5AAKT1KDM4E
SCHEMBL22367672 0.74 SRC (0.63) SRCINPPL1INPP5AAKT1KDM4E
SCHEMBL9789635 0.74 TTR (0.49) KDM4EHSD17B10TTRALDH1A1HPGD
SCHEMBL28786310 0.73 INPPL1 (0.61) SRCINPPL1INPP5AAKT1KDM4E
SCHEMBL10931576 0.73 LTA4H (0.55) KDM4EHSD17B10TTRALDH1A1HPGD
SCHEMBL19205830 0.73 LTA4H (0.55) KDM4ETTRALDH1A1HPGDCTNNB1
SCHEMBL982183 0.72 ALDH1A1 (0.47) KDM4EHSD17B10TTRALDH1A1HPGD
SCHEMBL980809 0.70 TTR (0.45) KDM4EHSD17B10TTRALDH1A1HPGD
SCHEMBL4960202 0.70 TTR (0.47) KDM4EHSD17B10TTRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024476-A diphenylphosphonooxy-X-phenol compound, preparation method and application in preparation of aspartame 西北工业大学 2023-11-10 CN disclosed