SCHEMBL4960202

SCHEMBL4960202

Oc1c(Oc2ccccc2)ccc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.47
LTA4H P09960 2/20 0.46
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
TSHR P16473 1/20 0.46
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 1/20 0.42
CTNNB1 P35222 1/20 0.41
KMT2A Q03164 2/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
CAMK2A Q9UQM7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9789635 0.88 TTR (0.49) TTRLTA4HNR1H2BAXTSHR
SCHEMBL9768120 0.86 LTA4H (0.55) TTRLTA4HNR1H2BAXTSHR
SCHEMBL19205830 0.81 LTA4H (0.55) TTRLTA4HNR1H2BAXTSHR
SCHEMBL982234 0.81 TTR (0.50) TTRLTA4HNR1H2BAXTSHR
SCHEMBL2916124 0.79 LTA4H (0.52) TTRLTA4HNR1H2BAXTSHR
SCHEMBL8720652 0.79 LTA4H (0.58) TTRLTA4HNR1H2BAXTSHR
SCHEMBL8582074 0.78 TTR (0.52) TTRLTA4HNR1H2BAXTSHR
SCHEMBL982183 0.77 ALDH1A1 (0.47) TTRLTA4HNR1H2BAXTSHR
SCHEMBL9780873 0.77 LTA4H (0.55) LTA4HNR1H2BAXTSHRALDH1A1
SCHEMBL28177362 0.77 LTA4H (0.55) TTRLTA4HNR1H2BAXTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR TTR 927/4885LTA4H 2285/4885NR1H2 2546/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT TTR 121/4885LTA4H 2769/4885NR1H2 4848/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 TTR 280/4885LTA4H 974/4885NR1H2 2488/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 TTR 1675/4885LTA4H 1153/4885NR1H2 4694/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH TTR 2182/4885LTA4H 457/4885NR1H2 2961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.