SCHEMBL2910937

SCHEMBL2910937

CC(C)(C)c1cc(CCCO)cc(-c2ccccc2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TNKS2 Q9H2K2 1/20 0.45
ALDH1A1 P00352 5/20 0.41
MAPK1 P28482 2/20 0.41
GSR P00390 2/20 0.41
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 4/20 0.41
TSHR P16473 3/20 0.41
GMNN O75496 1/20 0.41
GABBR2 O75899 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2913632 0.87 TNKS2 (0.44) GAAMEN1KMT2ATNKS2ALDH1A1
SCHEMBL2679807 0.84 MEN1 (0.51) GAAMEN1KMT2AALDH1A1MAPK1
SCHEMBL2914750 0.84 TNKS2 (0.51) TNKS2ALDH1A1HPGDALOX15PTPN1
SCHEMBL2414760 0.82 ALDH1A1 (0.56) GAAMEN1KMT2ATNKS2ALDH1A1
Methane SCHEMBL27710180 0.81 ALDH1A1 (0.55) GAAMEN1KMT2ATNKS2ALDH1A1
SCHEMBL2916168 0.80 TNKS2 (0.49) GAAMEN1KMT2ATNKS2LMNA
SCHEMBL2679896 0.79 MEN1 (0.47) GAAMEN1KMT2AALDH1A1MAPK1
SCHEMBL28280389 0.79 GAA (0.51) GAAMEN1KMT2AALDH1A1HTT
SCHEMBL14002954 0.78 TSHR (0.48) GAAMEN1KMT2ATNKS2ALDH1A1
SCHEMBL2910800 0.78 TNKS2 (0.44) GAAMEN1KMT2ATNKS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
CN-1307139-C Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2007-03-28 CN disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
CN-1448379-A Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2003-10-15 CN disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 GAA 4341/4885MEN1 4744/4885KMT2A 3167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.