Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679807 | 0.84 | MEN1 (0.51) | MEN1KMT2AGAABACE1ALDH1A1 | |
| SCHEMBL38917 | 0.81 | CA2 (0.55) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL25446710 | 0.80 | BACE1 (0.47) | MEN1KMT2ABACE1ACLYALDH1A1 | |
| SCHEMBL2910937 | 0.79 | GAA (0.47) | MEN1KMT2AGAABACE1ALDH1A1 | |
| SCHEMBL9169045 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL23239220 | 0.79 | BACE1 (0.46) | MEN1KMT2ABACE1ACLYALDH1A1 | |
| SCHEMBL28280389 | 0.79 | GAA (0.51) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL510694 | 0.77 | CA2 (0.59) | MEN1KMT2AGAABACE1ALDH1A1 | |
| SCHEMBL4575808 | 0.77 | CA1 (0.62) | MEN1KMT2AGAABACE1ALDH1A1 | |
| SCHEMBL21753677 | 0.76 | CA2 (0.57) | MEN1KMT2AGAABACE1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662351-B1 | Alkylated heterocyclic reaction products useful as antioxidants | SI GROUP INC (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-2084142-B1 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | SI GROUP INC (US) | 2016-03-23 | — | — | EP | disclosed |
| EP-2079677-B1 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | ALBEMARLE CORP (US) | 2014-07-09 | — | — | EP | disclosed |
| EP-2662351-A1 | Alkylated heterocyclic reaction products useful as antioxidants | Albemarle Corporation (US) | 2013-11-13 | — | — | EP | disclosed |
| US-8455414-B2 | Macromolecular amine-phenolic antioxidant compositions, process technology thereof, and uses thereof | ALBEMARLE CORPORATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-8410084-B2 | Alkylated heterocyclic reaction products useful as antioxidants | ALBEMARLE CORPORATION (US) | 2013-04-02 | — | — | US | disclosed |
| US-20120115764-A1 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | ALBEMARLE CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |
| US-20100041730-A1 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | ADDIVANT USA, LLC | 2010-02-18 | — | — | US | disclosed |
| EP-2084142-A2 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | Albermarle Corporation (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-2079677-A2 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | Albermarle Corporation (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2009073378-A1 | INDUSTRIAL OIL FORMULATIONS CONTAINING MACROMOLECULAR ANTIOXIDANTS | ALBEMARLE CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2008048988-A2 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | ALBEMARLE CORPORATION (US) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008048989-A2 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | ALBEMARLE CORPORATION (US) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008048990-A2 | PROCESSES SUITABLE FOR PRODUCING MACROMOLECULAR ANTIOXIDANT COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115764-A1 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | PNMT, COMT, MAOA | MEN1 3595/4885KMT2A 668/4885GAA 1654/4885 |
| US-20100041730-A1 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | GPX4, AOX1, SQOR | MEN1 3802/4885KMT2A 3567/4885GAA 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.