Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.55 |
| ▸ | FLT3 | P36888 | 4/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852518 | 0.81 | DYRK1A (0.56) | DYRK1ADYRK1BDYRK2DYRK3CCNT1 | |
| SCHEMBL2650330 | 0.78 | FLT3 (0.74) | MIFDYRK1ADYRK1BFLT3PIK3CA | |
| SCHEMBL73247 | 0.78 | BACE1 (0.62) | MIFDYRK1ADYRK1BDYRK2DYRK3 | |
| SCHEMBL29109646 | 0.78 | FLT3 (0.69) | MIFDYRK1ADYRK1BFLT3PIK3CA | |
| SCHEMBL73445 | 0.78 | MIF (0.60) | MIFDYRK1ADYRK1BDYRK2DYRK3 | |
| SCHEMBL14138786 | 0.78 | MIF (0.60) | MIFDYRK1ADYRK1BFLT3PIK3CA | |
| SCHEMBL30655418 | 0.78 | FLT3 (0.69) | MIFDYRK1ADYRK1BFLT3PIK3CA | |
| SCHEMBL23330745 | 0.76 | FLT3 (0.51) | MIFDYRK1AFLT3PIK3CAKDR | |
| SCHEMBL16675756 | 0.74 | MIF (0.59) | MIFFLT3CHEK1 | |
| SCHEMBL72363 | 0.74 | IRAK4 (0.61) | MIFDYRK1ADYRK1BFLT3PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | MIF 2367/4885DYRK1A 3453/4885DYRK1B 3272/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | MIF 2367/4885DYRK1A 3453/4885DYRK1B 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.