Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LIPA | P38571 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100097 | 1.00 | LMNA (0.33) | LMNATSHRCCR2CYP2C19LIPA | |
| SCHEMBL10989977 | 0.94 | ARG1 (0.33) | LMNATSHR | |
| SCHEMBL3424293 | 0.94 | ARG1 (0.33) | LMNATSHR | |
| SCHEMBL4634034 | 0.94 | ARG1 (0.33) | LMNATSHR | |
| SCHEMBL10659624 | 0.94 | ARG1 (0.33) | LMNATSHR | |
| Hydrochloric Acid SCHEMBL3418562 | 0.93 | ARG1 (0.32) | — | |
| SCHEMBL5791673 | 0.91 | LMNA (0.33) | LMNATSHRLIPA | |
| SCHEMBL15664981 | 0.86 | ARG1 (0.34) | — | |
| SCHEMBL31105161 | 0.86 | SLC6A1 (0.32) | LMNATSHR | |
| Hydrochloric Acid SCHEMBL25348463 | 0.85 | ARG1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126101-A | Efficient preparation method of hydrochloride intermediate with proline structure | 瑞博(杭州)医药科技有限公司 | 2023-11-28 | — | — | CN | disclosed |