Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.47 |
| ▸ | RET | P07949 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12079225 | 0.82 | NR3C1 (0.44) | NR3C1RETPIK3CDPIK3CAPIK3CG | |
| SCHEMBL18642033 | 0.73 | JAK2 (0.42) | RETPIK3CDPIK3CAPIK3CGCSNK1A1 | |
| SCHEMBL1742197 | 0.73 | PDE9A (0.54) | PDE9APDE1C | |
| SCHEMBL30612643 | 0.69 | PDE10A (0.36) | PIK3CDCSNK1A1CSNK1DCSNK1EPDE9A | |
| SCHEMBL20971222 | 0.68 | HCAR1 (0.42) | PIK3CDPIK3CAPDE9APDE1C | |
| SCHEMBL17870121 | 0.68 | NR3C1 (0.39) | NR3C1CSNK1A1BTK | |
| SCHEMBL19917153 | 0.68 | ADAMTS5 (0.37) | NR3C1RETPIK3CDPIK3CAPIK3CG | |
| SCHEMBL17963092 | 0.66 | NR3C1 (0.61) | NR3C1 | |
| SCHEMBL31725442 | 0.65 | PDE1C (0.40) | NR3C1PIK3CDPIK3CAPIK3CGCSNK1A1 | |
| SCHEMBL20413442 | 0.64 | NR3C1 (1.00) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166161-B | Compounds having PDE9A inhibiting activity and pharmaceutical uses thereof | 韩国化学研究院 | 2023-10-27 | — | — | CN | disclosed |