Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALPL | P05186 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776048 | 0.81 | KDM4E (0.67) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL12824407 | 0.79 | KDM4E (0.71) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL580823 | 0.78 | KDM4E (0.75) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL31268013 | 0.78 | KDM4E (0.75) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL6101938 | 0.76 | KDM4E (0.59) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL4028475 | 0.76 | KDM4E (0.59) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL7964553 | 0.76 | KDM4E (0.59) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL1414907 | 0.76 | KDM4E (0.60) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL9486704 | 0.76 | KDM4E (0.59) | KDM4ETDP1ALDH1A1TP53ALOX15 | |
| SCHEMBL8891318 | 0.76 | KDM4E (0.65) | KDM4ETDP1ALDH1A1TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966184-B1 | PYRIDINYL-QUINAZOLINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-08-25 | — | — | EP | disclosed |
| US-20090306102-A1 | 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES | NEUROSEARCH A/S (DK) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306102-A1 | 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES | KCNJ2, KCNQ1, KCNK2 | KDM4E 1023/4885TDP1 3156/4885ALDH1A1 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.