Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379332 | 0.85 | PSIP1 (0.40) | NPSR1PSIP1TP53PRSS1PRSS2 | |
| SCHEMBL6380236 | 0.81 | TDP1 (0.41) | NPSR1PSIP1ALDH1A1TSHRMEN1 | |
| SCHEMBL6378855 | 0.80 | MMP9 (0.40) | ALDH1A1 | |
| SCHEMBL6379705 | 0.78 | MMP9 (0.43) | FAAHALDH1A1 | |
| SCHEMBL11210092 | 0.78 | MMP9 (0.43) | FAAHALDH1A1 | |
| SCHEMBL29116411 | 0.77 | PSIP1 (0.46) | NPSR1PSIP1ALDH1A1POLBCYP2D6 | |
| SCHEMBL10864478 | 0.77 | PSIP1 (0.46) | NPSR1PSIP1ALDH1A1POLBCYP2D6 | |
| SCHEMBL9807345 | 0.76 | PRSS1 (0.40) | NPSR1PRSS1PRSS2PRSS3F2 | |
| SCHEMBL5512811 | 0.76 | NOS3 (0.45) | NPSR1ALDH1A1CYP2D6NOS3NOS1 | |
| SCHEMBL5513115 | 0.76 | CYP2A6 (0.47) | NPSR1PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333656-A1 | Reactive dyes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | claimed |
| US-8252814-B2 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-28 | — | — | US | disclosed |
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISHIHARA YUJI | 2009-10-22 | — | — | US | disclosed |
| US-20090054411-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | US | disclosed |
| EP-2010496-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | AstraZeneca AB (SE) | 2009-01-07 | — | — | EP | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| EP-1891954-A2 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2008-02-27 | — | — | EP | disclosed |
| WO-2007119046-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | disclosed |
| US-20070232538-A1 | Uses of polypeptides | TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) | 2007-10-04 | — | — | US | disclosed |
| US-4296199-A | CONTAINING A CYAN COLOR FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1981-10-20 | — | — | US | disclosed |
| US-4294918-A | CONTAINING A COLORLESS CYAN COLOR FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1981-10-13 | — | — | US | disclosed |
| US-4283486-A | DISCOLORATION INHIBITION | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4264722-A | A COLORLESS CYAN-COLOR-FORMING COUPLER COMPRISING 4-OXY-DERIVATIVES OF 1-HYDROXY-2-SEC-AMIDO-NAPHTHALENE OR BENZENE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| EP-0024033-A1 | Photographic colour couplers and light-sensitive material containing them | FUJI PHOTO FILM CO., LTD. (JP) | 1981-02-18 | — | — | EP | disclosed |
| US-4228233-A | CYAN DYE FORMING, COLORLESS COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4123281-A | Photographic silver halide color material containing fast-acting hardener and 2-pyrazolin-5-one coupler precursors | AGFA-GEVAERT N.V. (BE) | 1978-10-31 | — | — | US | disclosed |
| US-4083721-A | AROMATIC PRIMARY AMINE DEVELOPER | FUJI PHOTO FILM CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-4072525-A | COLOR PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-07 | — | — | US | disclosed |
| US-4032345-A | SILVER HALIDE MATERIALS CONTAINING PHOTOGRAPHIC COLOR COUPLERS WITH ISOTHIOCYANATO GROUPS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BCHE, PDE7A | NPSR1 2463/4885PSIP1 1915/4885TP53 2950/4885 |
| US-20070232538-A1 | Uses of polypeptides | NPSR1, SCTR, GRPR | NPSR1 1/4885PSIP1 1935/4885TP53 3428/4885 |
| US-20090054411-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | CSF1R, CSF3R, FLT3 | NPSR1 1241/4885PSIP1 2632/4885TP53 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.