Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29115107 | 0.90 | KMT2A (0.56) | SMN1; SMN2KMT2AMEN1NOD2ALDH1A1 | |
| SCHEMBL29114964 | 0.86 | MAPT (0.53) | SMN1; SMN2KMT2AMEN1NOD2ALDH1A1 | |
| SCHEMBL29115001 | 0.81 | CYP1A2 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL30683706 | 0.78 | LMNA (0.53) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL29114917 | 0.78 | LMNA (0.53) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL3450312 | 0.74 | POLB (0.56) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL12993897 | 0.73 | NR1H4 (0.80) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL29114967 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AALDH1A1LMNAPKM | |
| SCHEMBL2936661 | 0.72 | ALDH1A1 (0.78) | SMN1; SMN2KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL4390142 | 0.72 | HPGD (0.71) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143019-A | As beta 2 Pyrazole amide derivatives of allosteric antagonists of the adrenergic receptors | 常州大学 | 2023-12-01 | — | — | CN | disclosed |