Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114917 | 1.00 | LMNA (0.53) | LMNAACKR3CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29114956 | 0.93 | PTPN1 (0.53) | LMNAACKR3MEN1KMT2AMAPT | |
| SCHEMBL29114941 | 0.90 | POLB (0.50) | LMNAACKR3MEN1KMT2AMAPT | |
| SCHEMBL29114965 | 0.84 | DYRK1A (0.51) | ACKR3CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL29115001 | 0.83 | CYP1A2 (0.53) | LMNACYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL29114964 | 0.80 | MAPT (0.53) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29114946 | 0.78 | SMN1; SMN2 (0.54) | LMNAMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7664413 | 0.76 | CYP1A2 (0.67) | LMNAACKR3CYP1A2CYP2C19MEN1 | |
| SCHEMBL29114968 | 0.75 | SMN1; SMN2 (0.61) | LMNAMEN1KMT2AMAPTHPGD | |
| SCHEMBL18300810 | 0.73 | LMNA (0.59) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143019-A | As beta 2 Pyrazole amide derivatives of allosteric antagonists of the adrenergic receptors | 常州大学 | 2023-12-01 | — | — | CN | disclosed |